THEFERMANATOR
God
I haven't done it yet, but I don't see why I couldn't. As long as I find a ramp with plenty of maneuvering room, it should be fine.
KNIGHTS KEY/MARATHON has a real nice RV park with a marina basin right on US1 just before the 7 mile bridge. I believe they have a tractor for launching your boat for you as well since they cater to RVers with boats.